Echinacea purpurea is one of the most used herbal products with published evidence in the prevention and shortening of the duration of common cold, flu and Upper respiratory tract infection. Echinacosides in Echinaflu® stimulates T-lymphocyte and interferon production; inhibit hyaluronidase. Additionally, results from Echinacea supplementation in human trial were largely consistent with a decrease in the pro-inflammatory cytokines that play a role in the progression of cytokine storm and Acute Respiratory Distress Syndrome (ARDS), factors that play a significant role in the death of COVID-19 patients. Zinc is a Cofactor in over 100 enzymes it plays a role in DNA synthesis; supports a healthy immune system; helps maintain a sense of smell and taste; may assist in proper function of insulin. Zinc and vitamins C are part of the integral parts of the immune system. Therefore, adequate levels of this key nutrients have been shown to acting in synergy preserve the mucosal epithelial cells, possibly making them less susceptible to pathogen entry, such as SARS-CoV-2. Echinaflu therefore has a comprehensive oversight and control of common cold and flu incidences and symptoms.